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Sedating dose

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At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes.

Doses of sedatives such as benzodiazepines, when used as a hypnotic to induce sleep, tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.

There is some overlap between the terms "sedative" and "hypnotic".

Medications that elicit pharmacologic effects, such as anxiolysis, amnesia, or analgesia, provide patient comfort during various procedures.

I would honestly recommend you find a better drug for comedowns. I had answered the same exact question the very same day, I was kinda irritated Yeah, 12.5-50mg is best for sleep, as it doesn't act as an anti-psychotic at that dosage, but rather as a sedating anti-cholinergenic, in which case Doxylamine gives similar anti-cholingergenic effects without the shitstorm of side effects Seroquel will bring you.

You really don't want to be messing with seroquel if you don't need it. I was on Quetiapine (seroquel) for 2 years as part of my maintenance bipolar treatment. I hate the stuff, but to answer your question: I started on 200mg xr once a day - I could not function, all I wanted to do was sleep.

So long story short - if you you are just using seroquel for sleep then any dose between 25-200mg should help you. I get benzos usually An antipsychotic taken after an amphetamine is going to be or seem especially sedating, as it will cease all dopamine activity and essentially kill the high all together.

You can take more than that but it might not make you any more tired. so it it isnt more sedating in lower doses than but it plateaus at about 300mg is that right? You shouldn't need more than 50mg for comedown/sleep.